Johnny Depp (1963 - )
- A Nightmare on Elm Street (1984) [Glen Lantz]: Killed (off-screen) when Robert Englund pulls him down into his bed after he falls asleep; we see Robert grab him and pull him down, followed by a fountain of blood gushing from the bed. (There is a deleted scene where his body is lifted up into the air before being dropped down again.) He later reappears in Heather Langenkamp's dream.
- Platoon (1986) [Private Lerner]: Mortally wounded in combat with the Viet Cong; the movie doesn't actually confirm that he's killed, but he's so badly wounded that it seems a safe assumption.
- Ed Wood (1994) [Edward D. Wood Jr.]: Dies (off-screen) of a heart attack, several years after the story ends; his death is mentioned in the on-screen text at the end of the movie.
- Dead Man (1995) [William Blake]: Mortally wounded in a shoot-out with Lance Henriksen; he dies after Gary Farmer lays him out in a canoe and sets him adrift for his final journey.
- The Astronaut's Wife (1999) [Commander Spencer Armacost]: Electrocuted when Charlize Theron throws an appliance into the water when he's standing on the flooded floor, in an attempt to destroy the alien possessing him (only for said alien to then possess her as he dies).
- From Hell (2001) [Inspector Fred Abberline]: Dies (off-screen) of an overdose in an opium den; his body is shown afterwards when Robbie Coltrane comes to get him and discovers that he's dead. (Historically inaccurate, the real inspector Abberline died from old age in 1929).
- Pirates of the Caribbean: Dead Man's Chest (2006) [Captain Jack Sparrow]: Eaten by the Kraken, after Keira Knightly chains him to the mast of his ship. He is brought back to life by Geoffrey Rush, Keira and the other pirates in the sequel Pirates of the Caribbean: At World's End.
- Pirates of the Caribbean: At World's End (2007) [Captain Jack Sparrow]: In one of his imagination sequences of several different "Jack Sparrows", one is shot by another. (real one, survives the film obviously).
- Sweeney Todd: The Demon Barber of Fleet Street (2007) [Sweeney Todd]: Throat slit with his own razor by Ed Sanders as he cradles his wife's (Laura Michelle Kelly) body in his arms.
- Public Enemies (2009) [John Dillinger]: Shot repeatedly by Stephen Lang and other FBI agents as he is leaving a movie theater; he dies shortly afterwards while talking to Stephen.
- 21 Jump Street (2012) [Tom Hanson]: Shot to death, along with Peter DeLuise, by DeRay Davis and his men while he is talking to Jonah Hill and Channing Tatum; he and Peter die shortly afterwards while talking to each other. (Played for comic effect.)
- Into the Woods (2014) [Wolf]: Stabbed in the stomach (off-screen) by James Corden in order to free Lilia Crawford and Annette Crosbie from his stomach after he had eaten them.
- Transcendence (2014) [Dr. Will Caster]: Dies from radiation poisoning after being shot with radioactive bullets by Lukas Haas. His mind is uploaded into a computer program in order to keep it alive and he later forms a new body via nanotechnology. He is later seemingly destroyed when he allows a virus created by Paul Bettany to be downloaded into him by a dying Rebecca Hall. His body is later seen lying over Rebecca when Paul enters their compound. (it's implied that his mind along with Rebecca's lives on)
- Ex-Mr. Amber Heard.
- Godfather of Tim Burton and Helena Bonham Carter's children.